Prevalence of Mycobacterium Tuberculosis Strains and Rifampicin Mono-resistance in Newly Diagnosed Cases from East Maharashtra Region

Introduction: Tuberculosis (TB) is one of the major causes of morbidity and mortality worldwide. Also MDR-TB and HIV-TB co-infection are major hurdles in achieving aim and objective of national tuberculosis programme. Material and method: this retrospective study included 1364 suspected patients from April 2016 to March 2017 from registered RNTCP patients. The samples were subjected to Xpert MTB/RIF Assay. Data was tabulated and analyzed using spss 16. Results: out of total 1364 suspected TB cases, 155 (11.36%) were detected with mycobacterium tuberculosis, whereas 1209 (88.64%) were negative for tuberculosis. Out of 155 tuberculosis patients, 64 (41.29%) were HIV positive, 59 (38.06%) had extra-pulmonary TB, 8 (5.16%) were children and 24 (15.48%) were other clinically tested. 64 (7.56%) patients have HIV-TB co-infection. Out of total 155 conrmed TB cases, 7 (4.516%) patients had rifampicin resistance Conclusion: Prevalence of mycobacterium tuberculosis and rifampicin resistance is found to be high suggesting need of awareness about the condition and its spread.